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What is Janumet?

Janumet is a combination medication that is used alongside diet and exercise to improve blood sugar control in adults with type 2 diabetes. Janumet contains metformin and sitagliptin to control high blood sugar. Metformin works by helping restore your body’s proper response to the insulin you naturally produce and decreases the amount of sugar that your liver makes and that your stomach and intestines absorb. The other medication sitagliptin works by increasing the levels of incretins which increase insulin release after a meal helping to control your blood sugar.

Always read the patient information and instructions carefully before using this medication.

• Janumet should be taken orally with meals and is typically taken twice daily. Unless advised by your doctor otherwise, you should drink plenty of fluids while taking Janumet.
• The manufacturer of this drug advises not to split, break or cut the tablet before taking it.
• Your Janumet dosage is based on your medical condition, other medications you take and your response to treatment. Do not change or increase your Janumet dosage unless advised by a doctor. Your doctor may start you at a low dose of this medication and gradually increase your dose to reduce the risk of side effects.
• Janumet is most effective when it is taken regularly. Try to take it at the same time each day.
• If you already take another diabetes drug, make sure to follow your doctor’s instructions about whether to stop or continue taking any other drugs.
• Always check your blood sugar regularly and track your results. Your dosage or treatment may need to be adjusted.

Make sure to tell your doctor and pharmacist:

• If you have any drug allergies.
• Which other prescription and non-prescription medications you currently take.
• Your medical history, especially of breathing problems, blood problems, kidney disease, liver disease, pancreas disease or gallstones.
• If you are breast feeding.

Also be aware that:

• You may experience blurred vision, drowsiness or dizziness due to low or high blood sugar. You should not drive, operate machinery or do any other activity requiring alertness until it can be done safely.
• You should limit your alcohol intake while using Janumet as it can increase your risk of lactic acidosis and low blood sugar.
• Make sure to drink lots of fluids while taking this medication to prevent dehydration.
• Older adults may be more sensitive to the side effects of Janumet.
• Janumet should only be used when clearly needed during pregnancy. Your doctor may want to change your medication.
• This medication may cause you changes in the menstrual cycle, increasing the risk of pregnancy.
• Avoid drinking alcohol while taking this medication as it can lower blood sugar and may increase your risk of lactic acidosis.

Common Janumet side effects may include but are not limited to:

• Low blood sugar.
• Upset stomach, diarrhea, gas, nausea or vomiting.
• Cold symptoms including runny or stuffy nose, headache, weakness, sneezing or sore throat.

Stop taking this medicine and get emergency help if you show symptoms of lactic acidosis such as muscle pain, feeling cold, breathing problems, dizziness, lightheadedness, tiredness, feeling very weak, stomach pain, slow or irregular heartbeat, stomach pain or nausea with vomiting.

Contact your doctor if you experience any of the following Janumet side effects:

• Itching, blisters or a breakdown of the outer layer of skin.
• Ongoing or severe joint pain.
• Little or no urination.
• Shortness of breath.
• Swelling in your legs or feet or rapid weight gain.
• Signs of low blood sugar such as headache, sleepiness, dizziness, sweating, hunger, fast heartbeat or feeling jittery.

Q: What should I do if I miss a dose of Janumet?

A: Take your missed dose with food as soon as you remember. If it is almost time for the next dose then skip your missed dose. Do not take extra medication to make up for a missed dose.

Q: Can I take alcohol with Janumet?

A: Avoid drinking alcohol while taking this medication as it can lower blood sugar and may increase your risk of lactic acidosis.