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What is Androcur (cyproterone)?

Androcur contains cyproterone acetate and is used to control hypersexuality or sexual deviation in men. Androcur can be used in anti-androgen therapy because it blocks and reduces the male sex hormones (androgens) produced by the body. Androcur may be prescribed if your doctor considers other interventions inappropriate. This drug can reduce sperm production and cause abnormally shaped sperm. You may be asked to sign a witnessed agreement to treatment before being prescribed Androcur.

Refer to the package leaflet before taking this drug
Always take this medicine exactly as instructed by your doctor

  • Androcur is taken as a tablet
  • It should be swallowed whole with a drink of water
  • Take after your morning and your evening meal
  • A typical dosage for Androcur is 1 tablet, twice a day
  • Tell your doctor immediately if you take more than you should


Before taking Androcur (cyproterone), tell your doctor:

  • If you are undergoing treatment for tuberculosis
  • If you are using epilepsy medicine such as phenytoin
  • If you regularly take herbal remedies like St. John’s wort (hypericum perforatum)
  • If you are taking fungal condition medicines like ketoconazole, itraconazole, or clotrimazole
  • If you are on ritonavir to treat HIV infections
  • If you are on statins to lower cholesterol
  • If you are taking diabetes medicine like glitazones

Do not take Androcur if you have:

  • Liver diseases, including previous or existing tumors, Dubin-Johnson syndrome, or Rotor syndrome
  • Cancer
  • Meningioma
  • Unintentionally lost weight or muscle recently
  • Blood clots
  • Severe diabetes that affects blood circulation
  • Sickle-cell anemia
  • Severe depression

Do not take this drug if you are:

  • Allergic to cyproterone acetate or any other Androcur ingredient
  • Under 18 years old or if your bones or testes are not yet fully developed

Side Effects of Androcur

Common side effects:

  • Reduced sperm count
  • Reduced volume of ejaculate

Rarer side effects that may require a doctor’s attention:

  • Rash, itching, or other signs of an allergic reaction
  • Shortness of breath or trouble swallowing
  • Breast lumps or oozing fluid from the nipples
  • Meningioma


What will happen if I stop using Androcur?

After stopping treatment with Androcur (cyproterone), your sperm count and breast swelling will typically return to normal. If you experience any side effects while stopping treatment, report them to your doctor. It can take 3 to 20 months for fertile sperm production to re-establish after stopping treatment with Androcur.

How long does Androcur take to work?

Androcur (cyproterone) will typically reduce sexual desire and erectile function within the first week of treatment. Maximum effect of Androcur occurs around the third or fourth week. After taking Androcur for some months, you will likely be unable to make anyone pregnant. However, you should not rely on Androcur for contraception.

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