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What is Rybelsus?

Rybelsus is an oral medication used to treat type 2 diabetes. It contains semaglutide, which is a GLP-1 receptor agonist. Essentially, Rybelsus works by increasing the body's insulin release in order to decrease blood sugar levels. Rybelsus also slows down gastric emptying, a process that moves food through the stomach. This further helps with lowering overall blood sugar levels.

One study found that Rybelsus lowers blood sugar more effectively than a placebo. In this study, researchers found that Rybelsus helped lower hemoglobin A1c levels by 1.2 to 1.4 percent. Rybelsus is only approved for treating type 2 diabetes. The FDA does not approve Rybelsus for the treatment of type 1 diabetes or for weight loss.

Rybelsus is typically taken once daily, at least 30 minutes before the first meal. This medication should not be taken with food or any beverages. However, you may take it with plain water (no more than 4 ounces).

If you take other medications, make sure to take Rybelsus at least 30 minutes before your other pills. Leaving time between medications allows for Rybelsus to work properly. Taking Rybelsus at the same time each day can help you remember your dose. Consult your healthcare provider for more information on how to take Rybelsus.

Cautions

Rybelsus comes with a boxed warning from the FDA because it has been shown to cause tumors in the thyroid gland in animal studies. If you or someone in your family has a history of medullary thyroid carcinoma (MTC), Rybelsus may not be safe for you. Similarly, your doctor may tell you to avoid Rybelsus if you have endocrine neoplasia syndrome type 2. 

Other conditions that may increase the risk of complications with Rybelsus include pancreatitis, chronic kidney failure, and diabetic retinopathy. Additionally, your doctor may recommend avoiding Rybelsus if you are pregnant or breastfeeding, as it isn't known whether this medication is safe to take for current or expecting mothers.

Side Effects

Although Rybelsus does not cause side effects in everyone, it is important to know the potential side effects of this drug before starting treatment. The most common mild side effects of Rybelsus are weight loss, constipation, diarrhea, and belly pain. Nausea, vomiting, and a decreased appetite are also common. These milder side effects tend to go away on their own. However, we advise you to seek medical attention if your side effects worsen or last longer than a few weeks.

More severe side effects of Rybelsus include:

  • Pancreatitis
  • Diabetic retinopathy
  • Sudden kidney issues
  • Low blood sugar

Call your doctor right away if you experience any signs of the severe side effects listed above. Also, seek medical attention right away if you have an allergic reaction to semaglutide.

Rybelsus Prices in Canada

Patients in the United States often face significantly higher retail costs for Rybelsus.

Dosage

Canada Price (per tablet)

U.S. Retail Price (per tablet)*

Savings

3 mg

$10.48–$10.53

$25–$30

~60% less

7 mg

$10.64–$10.70

$28–$32

~65% less

14 mg

$11.74–$11.80

$32–$35

~65–70% less

*Based on typical U.S. retail prices without insurance.

Key Takeaway

Ordering Rybelsus from Canada can save patients over 60%, particularly when choosing 90-tablet quantities for long-term treatment.

How to Buy Rybelsus Online from Canada

Canada Drug Warehouse makes the process of ordering Rybelsus online simple and secure.

Steps to Order

  • Visit Canada Drug Warehouse and enter the medication name in the search bar.
  • Select your dosage and quantity, then click 'Add to Cart' and proceed to checkout.
  • Log in if you already have an account, or create a new one. Prefer to order by phone? Call 1-877-204-1506.
  • Upload your prescription online or ask us to contact your doctor or pharmacy.
  • Review your details and complete your order.
  • Your medication will be shipped directly to your door.

Why order from Canada?

Buying from a Canadian pharmacy allows patients to save money without compromising on quality or safety. Medications are dispensed only from licensed pharmacies with proper oversight.

Savings, Insurance, and FAQs

Does insurance cover Rybelsus?

Most U.S. insurance providers either do not cover Rybelsus or place it under high copay tiers. Ordering from Canada Drug Warehouse can help patients avoid these high out-of-pocket expenses.

Are discounts available for Rybelsus?

Yes. Patients can save more on Rybelsus when ordering larger quantities. Bulk pricing lowers the per-tablet cost, making long-term treatment more affordable.

How should Rybelsus be taken?

Rybelsus is taken once daily, at least 30 minutes before eating, drinking (other than plain water), or taking other medications. Swallow the tablet whole with up to 4 ounces of water.

What are the common side effects of Rybelsus?

Common side effects of Rybelsus include nausea, stomach upset, diarrhea, and decreased appetite. These often improve with continued use. Any severe or persistent side effects should be discussed with a healthcare provider.

How does Rybelsus work for weight loss?

Weight loss is a known side effect of Rybelsus. However, Rybelsus is not currently indicated for weight loss. Rybelsus is only approved to help lower blood sugar levels in those with type 2 diabetes.

Why is Rybelsus so expensive?

Rybelsus is an expensive diabetes medication because it is not available in a generic form yet. Rybelsus is also one of the leading brand-name drugs that utilizes semaglutide to help those with diabetes manage their blood sugar.

To save on Rybelsus, consider using an online Canadian pharmacy like Canada Drug Warehouse to fill your order. At Canada Drug Warehouse, we offer brand-name drugs and fast, discreet shipping at significant discounts.

What is Rybelsus used for?

Rybelsus is used for controlling blood sugar in adults with type 2 diabetes. Rybelsus contains the active ingredient semaglutide, which works by helping your body produce more insulin to convert food into energy.

How long does it take for Rybelsus to start working?

When you use Rybelsus as directed, you will typically feel the benefits of this drug after 30 days. It takes Rybelsus around one month of consistent use to reach a steady level in your system.

What happens if you take Rybelsus with food?

It is recommended that you take Rybelsus on an empty stomach to ensure proper absorption into your body. Taking Rybelsus with food may cause several complications. For example, it may prevent Rybelsus from working to its full effect, leading to blood sugar spikes and any accompanying symptoms.

Hear From People Like You

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Real People, Trustworthy Reviews

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Maya N

February 8, 2025

I used Canada drug Warehouse for the first time recently after using another Canadian company who kept raising the price- you have excellent customer service and some very helpful people…….thank you so much for your help.

Thomas L

January 7, 2025

Good

David H

October 2, 2024

Thank you

Linda C

January 9, 2023

I love Canada Drug Warehouse. They are super efficient and I like that they call me when one of my medications is about to expire. They have saved me thousands of dollars. This is a great company!!!!!!

James D

October 14, 2022

My prescription was received in 14 business days from the date of payment. The meds arrived in individual sealed pill packs. This was my first order and very pleased with their prompt and courteous service.

John H

October 1, 2022

Very informed and efficient agent taking order. Delivery when promised. Outstanding service.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

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Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1506 and a member of our CareTeam will be happy to assist you.

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Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.