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What is Estrogel?

Estrogel (estradiol) is a medication used to reduce symptoms of menopause such as hot flashes and vaginal dryness, burning and irritation. Estrogens are a female sex hormone made in the ovaries which regulate many body processes. Estrogel is absorbed through the skin and into the blood stream.

Always read the patient information and instructions carefully before using this medication.

  • Apply Estrogel to clean dry skin. Read the enclosed instructions for where to apply. Depending on the brand, it may be on the arm, shoulder or wrist.
  • Do not apply Estrogel to broken or irritated skin, or to the breast, face or in and around the vagina. You should apply this medication yourself and not allow others to apply it for you.
  • Your Estrogel dosage is based on your medical condition and your response to treatment. Do not change your dosage or the frequency applied unless advised by a doctor.
  • Wash your hands thoroughly with soap and water after applying this medication to reduce the risk of spreading it to other people. Wait around five minutes for the site to dry before dressing and cover the application site with clothing. Wait at least one to two hours before allowing others to touch the skin where the gel was applied. If someone touches the site before this time, they should immediately wash the area of their body with soap and water.
  • Do not wash or swim for at least two hours after applying.
  • Estrogel is most effective when used regularly. Try to use this medication at the same time each day.
  • Avoid getting Estrogel in your eyes. If it does get into your eyes, rinse them immediately with warm water.
  • Estrogel is flammable until dry. Do not smoke or go near an open flame until this medication is dried.
  • Tell your doctor if your condition does not improve or worsens.

Cautions

Make sure to tell your doctor and pharmacist:

  • If you have any drug allergies.
  • Which other prescription and non-prescription medications you currently take.
  • Your medical history especially of vaginal bleeding of an unknown cause, stroke, heart disease, liver disease, kidney disease, blood clotting disorders, high blood pressure, diabetes, high cholesterol, obesity, lupus, underactive thyroid, mineral imbalance, hypoparathyroidism, uterus problems, gallbladder disease, asthma, seizures, migraines, mental or mood disorders or porphyria.
  • Your personal and family history of breast lumps, cancer, blood clots or angioedema.
  • If you are breast feeding.

Also be aware that:

  • You should not smoke or use tobacco while using this medication. Smoking combined with estrogens can increase the risk of stroke, blood clots, high blood pressure and heart attack, especially in women over 35.
  • Tell your doctor if you are having or just had surgery or if you will be confined to a bed or chair for an extended period of time as these conditions can increase your risk of blood clots and may need to temporarily stop taking this medication or take special precautions.
  • Estrogel may cause dark or blotchy areas on your face and body which can be worsened by sunlight. Limit your time in the sun and wear protective clothing when outdoors. Avoid tanning booths and sunlamps. Sunscreen may affect the absorption of this medication on the applied areas.
  • If you wear contact lenses or are nearsighted, you may develop vision problems while using this medication. Speak to your eye doctor if this occurs.
  • Estrogel should not be used during pregnancy.
  • You should wait at least one to two hours before allowing others to touch the skin where the gel was applied. If someone touches the site before this time, they should immediately wash the area of their body with soap and water. If a child touches this area, they may occur side effects. Tell your doctor if you notice unexpected signs of puberty such as an increase in breast or nipple size.

Side effects of Estrogel

Common Estrogel side effects may include but are not limited to:

  • Headache or breast pain.
  • Vaginal itching, discharge, light bleeding or spotting.
  • Changes to your menstrual periods.
  • Thinning scalp hair.
  • Nausea, vomiting, bloating or stomach cramps.

Contact your doctor if you experience any of the following side effects of Estrogel:

  • Abnormal vaginal bleeding.
  • A lump in your breast.
  • Confusion, memory problems or concentration problems.
  • Signs of a heart attack such as chest pain or pressure, nausea, sweating or a pain spreading to your jaw or shoulder.
  • Signs of liver problems such as nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools or jaundice.
  • Signs of a stroke such as sudden numbness or weakness especially on one side of the body, sudden severe headache, slurred speech or vision or balance problems.
  • Signs of a blood clot in the lung such as chest pain, sudden coughing, wheezing, rapid breathing or coughing up blood.
  • Signs of a blood clot in your leg such as pain, swelling, warmth, or redness in one or both legs.
  • Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.

FAQs

Q: How long should I wait after applying Estrogel before washing?

A: Do not wash or swim for at least two hours after applying.

Q: What else is Estrogel called?

A: Estrogel is also known as Oestrogel. Oestrogel is not a generic alternative but the same brand name medication with a different name internationally.

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