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IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
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Buy Estrace (Estradiol) Online

Estrace is affordable and easy to buy with Canada Drug Warehouse. You can order your prescription medications online or call us 7 days a week and get your Estradiol delivered to your door for the fraction of the cost you usually pay.

What is Estrace?

Estrace (estradiol) is a medication which is used to treat symptoms of menopause such as hot flashes and vaginal dryness, as well as to prevent osteoporosis in menopausal women and to replace the estrogen in women with conditions which cause a lack of natural estrogen in the body.  

Always read the patient information and instructions carefully before using this medication.

  • Estrace should be taken orally. It can be taken with or without food although taking it with food or straight after a meal can prevent stomach upset.
  • Your estradiol dosage is based on your medical condition and your response to treatment. Do not change your dosage or the frequency this medication is taken unless advised by a doctor.
  • Estrace should be taken regularly to get the most benefit from it. Try to take it at the same time each day.
  • Tell your doctor if your condition does not improve or if it worsens.


Make sure to tell your doctor and pharmacist:

  • If you have any drug allergies.
  • Which other prescription and non-prescription medications you currently take.
  • Your medical condition especially of vaginal bleeding of an unknown cause, cancer, blood clots, stroke, heart disease, liver disease, kidney disease, blood clotting disorders, high blood pressure, diabetes, high cholesterol, obesity, lupus, underactive thyroid, mineral imbalance, hypoparathyroidism, uterus problems, gallbladder disease, asthma, seizures, migraines, porphyria and mental or mood disorders.
  • Your personal and family history of breast lumps, cancer, blood clots or angioedema.
  • If you will be having surgery of if you have just had surgery, or if you will be confined to a bed or chair for an extended period of time such as on a long flight. These conditions can increase your risk of a blood clot especially when taking estrogen.
  • If you are breast feeding. This medication can pass into breast milk and may affect the quantity and quality of the milk.

Also be aware that:

  • You should not smoke or use tobacco while taking Estrace. Smoking combined with estrogens can increase your risk of stroke, high blood pressure, blood clots and heart attack especially in women older than 35.
  • This medication can cause dark, blotchy areas on your face or skin. Sunlight can worsen this effect. Limit your time in the sun and wear protective clothing and sunscreen when outdoors. Avoid tanning booths and sunlamps.
  • If you wear contact lenses or are nearsighted, you may develop vision problems. Speak to your eye doctor if these problems happen.
  • This medication must not be used during pregnancy.
  • Children may be more sensitive to the side effects of this medication and can affect their growth or development. Monitor your child’s growth periodically.

Side effects of Estrace

Common Estrace side effects may include but are not limited to:

  • Nausea, vomiting, diarrhea or stomach cramps.
  • Sleep problems.
  • Mood changes.
  • Cold symptoms such as stuffy nose, sore throat or sinus pain.
  • Weight gain.
  • Headache, back pain or breast pain.
  • Thinning scalp hair.
  • Vaginal itching, discharge, change in menstrual periods or breakthrough bleeding.

Contact your doctor if you experience any of the following side effects of Estrace:

  • Signs of a heart attack such as chest pain or pressure, nausea, sweating, or pain spreading to your jaw or shoulder.
  • Signs of a stroke such as severe headache, slurred speech, problems with vision or balance, or sudden numbness or weakness especially on one side of the body.
  • Signs of a blood clot such as sudden vision loss, stabbing chest pain, shortness of breath, coughing up blood or pain or warmth in one or both legs.
  • Swelling or tenderness in your stomach.
  • Jaundice.
  • Memory problems, confusion or unusual behavior.
  • Pelvic pain or unusual vaginal bleeding.
  • Breast lumps.
  • Signs of a high levels of calcium such as nausea, constipation, vomiting, increased urination or thirst, muscle weakness, lack of energy or bone pain.
  • Signs of an allergic reaction such as hives, difficulty breathing or a swelling of your face, lips or throat.


Q: What should I do if I miss a dose of Estrace?

A: If you miss a dose of this medication, take it as soon as you remember. If it is almost time for your next dose, then skip your missed dose.

Q: What should I avoid while taking Estrace?

A: Avoid smoking as it can greatly increase your risk of blood clots, stroke and heart attack. Grapefruit and grapefruit juice can lead to unwanted side effects. Avoid grapefruit products.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1506 and a member of our CareTeam will be happy to assist you.

Call 1-877-204-1506
* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

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Great service. Drugs delivered on time and personnel are very helpful.
Sandra August 31, 2021

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Great service
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All good, as always
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Fast professional service
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Very excellent service.
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Frequent reminders help me order my prescription in time so I never run out!
George July 14, 2021

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Great service and support when I called with a concern.
Robert July 14, 2021

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Ordering was easy and smooth. Already placed a second order.
Patrick June 17, 2021

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I had one situation where my med did not make it to me. They corrected that by putting a tracking on it. I did get with no problem. I appreciate how your follow-up. Thank you
Alicia May 12, 2021

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I was very pleased with the service I received.
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