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What is Creon?

Creon (Pancreatic Enzyme) contains a combination of three enzymes (lipase, protease and amylase) which are usually produced by the pancreas and which are important for the digestion of sugars, fats and proteins. Creon 10 and 25 is used to replace these enzymes when the body does not have enough of its own or does not release enough into the small intestines due to cystic fibrosis, chronic inflammation of the pancreas or blockage of the pancreatic ducts.

Always read the patient information and instructions carefully before using this medication.

• Creon should be taken orally with meals or snacks.
• Swallow Creon capsules whole. Do not crush or chew capsules as this can irritate the mouth or change how the medication works.
• If swallowing capsules whole is difficult, then open the capsule and mix the contents in with a small amount of soft food (such as applesauce. Do not mix with alkaline food or liquid such as milk, tea or icecream). Drink a glass of water after taking Creon this way.
• Your Creon dosage is based on your medical condition, response to treatment, diet and weight. Do not change or increase your dosage unless advised by a doctor. Your condition will not improve quicker but you may increase the chance of side effects. Do not change brands of this medication without consulting with a doctor.
• Drink plenty of fluids while taking Creon 10 or Creon 25.
• This medication is most effective when taken regularly.

Make sure to tell your doctor and pharmacist:

• If you have any drug allergies.
• Which other prescription and non-prescription medications you currently take.
• Your medical history especially of sudden or severe swelling of the pancreas, pancrease disease, gout, kidney disease, high uric acid level blood or intestinal problems.
• If you are breast feeding.

Also be aware that:

• If you suffer from diabetes, this medication may affect your blood sugar. Your doctor may need to adjust your diabetes treatment.
• This medication should only be used when clearly needed during pregnancy.

Common Creon side effects may include but are not limited to:

• Stomach pain, gas or an upset stomach.
• Diarrhea, frequent or abnormal bowel movements.
• Coughing.
• Dizziness.
• Headaches.
• Weight loss.

Contact your doctor if you experience any of the following Creon side effects:

• Joint pain or swelling.
• Symptoms of a bowel disorder such as severe or unusual stomach pain, vomiting, bloating diarrhea or constipation.
• Signs of an allergic reaction such as hives, difficulty breathing or swelling of the face, throat or tongue.

Q: What should I do if I miss a dose of Creon?

A: If you miss a dose of Creon 10 or Creon 25, take the dose with your next meal or snack. Do not take extra medication to make up for a missed dose.