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Prescription Required
IMPORTANT NOTE: A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.
Difference between Brand & Generic?


What is Xifaxan?

Xifaxan is primarily an irritable bowel syndrome (IBS) medication. Containing the drug rifaximin, Xifaxan is an antibiotic which fights bacterial infection within your intestines. Xifaxan is unique in that it is not absorbed into your blood stream but passes into your intestines via your stomach. As well as treating IBS, Xifaxan is also prescribed to treat travelers’ diarrhea caused by E. coli and to prevent hepatic encephalopathy, a brain problem caused by liver disease. Xifaxan can only be used to treat bacterial infections and will not treat viral infections such as flu.


Always read the patient information and instructions carefully before using this medication.

  • Xifaxan can be taken with or without food.
  • Your doctor will dictate your Xifaxan dosage based on why it is being prescribed, your medical condition, response to treatment.
  • As an IBS treatment, Xifaxan is typically taken 3 times daily for 14 days.
  • As a traveler's diarrhea treatment, Xifaxan is usually taken every 8 hours. You should complete the full prescribed amount of antibiotics even when your symptoms have disappeared.
  • To prevent hepatic encephalopathy, this medication is normally taken twice daily.


Make sure to tell your doctor and pharmacist:

  • If you have any drug allergies.
  • Which other prescription and non-prescription medications you currently take.
  • Your medical history.
  • If you are breast feeding.

Also be aware that:

  • During pregnancy, Xifaxan should only be taken when clearly needed.
  • Live bacterial vaccines such as typhoid vaccine may be inneffective while taking Xifaxan therefore you should not have any immunizations or vaccinations while taking it.

Side Effects

Common Xifaxan side effects may include but are not limited to:

  • Swelling in your hands or feet.
  • Headaches, tiredness or dizziness.
  • Nausea. 
  • Abnormal liver function tests.

Contact your doctor if you experience any of the following side effects of Xifaxan:

  • Severe stomach pain.
  • Bloody or watery diarrhea. Tell your doctor even if this happens months after you finish taking Xifaxan.
  • Fluid buildup around the stomach such as rapid weight gain, stomach pain, bloating or breathing problems when lying down.


Q: Is Xifaxan an IBS medication?

A: Yes, Xifaxan is prescribed to treat irritable bowel syndrome (IBS) as well as traveler's diarrhea and hepatic encephalopathy.

Q: How much does Xifaxan cost?

A: The price of Xifaxan is based on if you buy the brand name or the generic alternative Rifaximin. You can get Xifaxan 550mg or Rifaximin in 550mg or 400mg. You don’t need a Xifaxan coupon to get our great prices.

Q: What should I do if I miss a dose of Xifaxan?

A: If you forget to take a dose of Xifaxan, take it as soon as you remember. If it is almost time for your next dose, then skip the missed dose. Do not take two doses at one time.

A valid Prescription is required to be mailed or faxed to complete this order. I acknowledge that I will need to be contacted to complete a health profile before my order is shipped.

Your Lowest Price, Guaranteed

Our goal is to bring you the most affordable medication. If you find a lower price advertised by another website or your local pharmacy, we’ll match that price or beat it by 10% of the difference.* Call us at 1-877-204-1506 and a member of our CareTeam will be happy to assist you.

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* Some exceptions may apply
Some exceptions may apply. To qualify for price matching, competitors must meet our standards for patient safety. Advertised prices must be for medication of the same type, strength, quantity, and form.

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just wanted to tell you that my wife and I are grateful for y'all. with my wife not being able to work, her meds were out of this world price wise we were struggling. then our Dr told us about y'all so we took a chance. Now she don't skip her med and we can afford them thank you very much to us you are a god sent thank you.
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I could not ask for more. The CDW is so easy to work with. People are friendly,helpful & knowledgeable. Thanks for being there for your customers. Prices are very reasonable. Mary P
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I just received my shipment today! Although it has taken longer than other options, the price value more than makes up for time. Everything that I ordered arrived in excellent shape. Definitely will re-order.
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great customer service. A+++
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Jessica fue muy amable , muchas gracias por su paciencia
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Very smooth process.
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Went well so far. Everyone I talked to were helpful. thanks, Jim
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Very easy to work with. Great prices.
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I am very pleased with the service and prices. I was glad they called me to remind to reorder. Thank you so much.
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Have enjoyed the prices of the products my husband and I receive from you...I do wish there was a savings on some other ones however...Our income takes a big hit on what our Doctors want us to take...Thank you for what you are able to do for us thus far though...
Sharon November 11, 2019
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